Simple and effective bacterial-based intratumoral cancer immunotherapy

BACKGROUND: We describe intratumoral injection of a slow-release emulsion of killed mycobacteria (complete Freund’s adjuvant (CFA)) in three preclinical species and in human cancer patients. METHODS: Efficacy and safety were tested in mammary tumors in mice, in mastocytomas in mice and dogs, and in...

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Detalles Bibliográficos
Autores principales: Carroll, Christina S E, Andrew, Erin R, Malik, Laeeq, Elliott, Kathryn F, Brennan, Moira, Meyer, James, Hintze, Alexander, Almonte, Andrew A, Lappin, Cassandra, MacPherson, Philip, Schulte, Klaus-Martin, Dahlstrom, Jane E, Tamhane, Rohit, Neeman, Teresa, Herbert, Elizabeth W, Orange, Maurice, Yip, Desmond, Allavena, Rachel, Fahrer, Aude M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Oncolytic and Local Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449973/
https://www.ncbi.nlm.nih.gov/pubmed/34531247
http://dx.doi.org/10.1136/jitc-2021-002688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449973/
https://www.ncbi.nlm.nih.gov/pubmed/34531247
http://dx.doi.org/10.1136/jitc-2021-002688

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