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A transferrable and integrative type I-F Cascade for heterologous genome editing and transcription modulation

The Class 1 type I CRISPR–Cas systems represent the most abundant and diverse CRISPR systems in nature. However, their applications for generic genome editing have been hindered due to difficulties of introducing the class-specific, multi-component effectors (Cascade) in heterologous hosts for funct...

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Detalles Bibliográficos
Autores principales:	Xu, Zeling, Li, Yanran, Cao, Huiluo, Si, Meiru, Zhang, Guangming, Woo, Patrick C Y, Yan, Aixin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450077/ https://www.ncbi.nlm.nih.gov/pubmed/34157103 http://dx.doi.org/10.1093/nar/gkab521

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