The beginning and the end: flanking nucleotides induce a parallel G-quadruplex topology

Genomic sequences susceptible to form G-quadruplexes (G4s) are always flanked by other nucleotides, but G4 formation in vitro is generally studied with short synthetic DNA or RNA oligonucleotides, for which bases adjacent to the G4 core are often omitted. Herein, we systematically studied the effect...

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Detalles Bibliográficos
Autores principales: Chen, Jielin, Cheng, Mingpan, Salgado, Gilmar F, Stadlbauer, Petr, Zhang, Xiaobo, Amrane, Samir, Guédin, Aurore, He, Fangni, Šponer, Jiří, Ju, Huangxian, Mergny, Jean-Louis, Zhou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450091/
https://www.ncbi.nlm.nih.gov/pubmed/34379785
http://dx.doi.org/10.1093/nar/gkab681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450091/
https://www.ncbi.nlm.nih.gov/pubmed/34379785
http://dx.doi.org/10.1093/nar/gkab681

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