Cargando…

Antisense ribosomal siRNAs inhibit RNA polymerase I-directed transcription in C. elegans

Eukaryotic cells express a wide variety of endogenous small regulatory RNAs that function in the nucleus. We previously found that erroneous rRNAs induce the generation of antisense ribosomal siRNAs (risiRNAs) which silence the expression of rRNAs via the nuclear RNAi defective (Nrde) pathway. To fu...

Descripción completa

Detalles Bibliográficos
Autores principales: Liao, Shimiao, Chen, Xiangyang, Xu, Ting, Jin, Qile, Xu, Zongxiu, Xu, Demin, Zhou, Xufei, Zhu, Chengming, Guang, Shouhong, Feng, Xuezhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450093/
https://www.ncbi.nlm.nih.gov/pubmed/34365510
http://dx.doi.org/10.1093/nar/gkab662