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Context-sensitivity of isosteric substitutions of non-Watson–Crick basepairs in recurrent RNA 3D motifs

Sequence variation in a widespread, recurrent, structured RNA 3D motif, the Sarcin/Ricin (S/R), was studied to address three related questions: First, how do the stabilities of structured RNA 3D motifs, composed of non-Watson–Crick (non-WC) basepairs, compare to WC-paired helices of similar length a...

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Detalles Bibliográficos
Autores principales: Khisamutdinov, Emil F, Sweeney, Blake A, Leontis, Neocles B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450098/
https://www.ncbi.nlm.nih.gov/pubmed/34403481
http://dx.doi.org/10.1093/nar/gkab703