Formation of artificial chromosomes in Caenorhabditis elegans and analyses of their segregation in mitosis, DNA sequence composition and holocentromere organization

To investigate how exogenous DNA concatemerizes to form episomal artificial chromosomes (ACs), acquire equal segregation ability and maintain stable holocentromeres, we injected DNA sequences with different features, including sequences that are repetitive or complex, and sequences with different AT...

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Detalles Bibliográficos
Autores principales: Lin, Zhongyang, Xie, Yichun, Nong, Wenyan, Ren, Xiaoliang, Li, Runsheng, Zhao, Zhongying, Hui, Jerome Ho Lam, Yuen, Karen Wing Yee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450109/
https://www.ncbi.nlm.nih.gov/pubmed/34417622
http://dx.doi.org/10.1093/nar/gkab690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450109/
https://www.ncbi.nlm.nih.gov/pubmed/34417622
http://dx.doi.org/10.1093/nar/gkab690

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