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The different biological effects of TMPyP4 and cisplatin in the inflammatory microenvironment of osteosarcoma are attributed to G‐quadruplex

OBJECTIVE: Osteosarcoma (OS) is characterized by high levels of the tumour‐associated inflammatory microenvironment. Moreover, in approximately 60% of OS, telomere length is maintained by alternative lengthening of telomeres (ALT) pathway. Whether the ALT pathway can be exploited for OS therapeutic...

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Detalles Bibliográficos
Autores principales: Chen, Jianqiang, Jin, Xiangxiang, Mei, Yanan, Shen, Zhe, Zhu, Jufan, Shi, Hongyi, Wang, Minshan, Zheng, Xiaohui, Liang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450119/
https://www.ncbi.nlm.nih.gov/pubmed/34296479
http://dx.doi.org/10.1111/cpr.13101