Inhibition of neuronal necroptosis mediated by RIP1/RIP3/MLKL provides neuroprotective effects on kaolin‐induced hydrocephalus in mice

OBJECTIVES: Necroptosis is widespread in neurodegenerative diseases. Here, we examined necroptosis in the hippocampus and cortex after hydrocephalus and found that a necroptosis pathway inhibitor alleviates necroptosis and provides neuroprotective effects. MATERIALS AND METHODS: Hydrocephalus was in...

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Detalles Bibliográficos
Autores principales: Liu, Chang, Chen, Yaxing, Cui, Wenyao, Cao, Yi, Zhao, Long, Wang, Haoxiang, Liu, Xiaoyin, Fan, Shuangmin, Huang, Keru, Tong, Aiping, Zhou, Liangxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450124/
https://www.ncbi.nlm.nih.gov/pubmed/34374150
http://dx.doi.org/10.1111/cpr.13108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450124/
https://www.ncbi.nlm.nih.gov/pubmed/34374150
http://dx.doi.org/10.1111/cpr.13108

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