Fine‐tuning of dual‐SMAD inhibition to differentiate human pluripotent stem cells into neural crest stem cells

OBJECTIVES: The derivation of neural crest stem cells (NCSCs) from human pluripotent stem cells (hPSCs) has been commonly induced by WNT activation in combination with dual‐SMAD inhibition. In this study, by fine‐tuning BMP signalling in the conventional dual‐SMAD inhibition, we sought to generate l...

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Detalles Bibliográficos
Autores principales: Kim, Hyun‐Mun, Noh, Hye Bin, Lee, Sang‐Hyuk, Lee, Kun‐Gu, Chang, Bomi, Cheong, Eunji, Lee, C. Justin, Hwang, Dong‐Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450125/
https://www.ncbi.nlm.nih.gov/pubmed/34323338
http://dx.doi.org/10.1111/cpr.13103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450125/
https://www.ncbi.nlm.nih.gov/pubmed/34323338
http://dx.doi.org/10.1111/cpr.13103

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