Cargando…
Fine‐tuning of dual‐SMAD inhibition to differentiate human pluripotent stem cells into neural crest stem cells
OBJECTIVES: The derivation of neural crest stem cells (NCSCs) from human pluripotent stem cells (hPSCs) has been commonly induced by WNT activation in combination with dual‐SMAD inhibition. In this study, by fine‐tuning BMP signalling in the conventional dual‐SMAD inhibition, we sought to generate l...
Autores principales: | Kim, Hyun‐Mun, Noh, Hye Bin, Lee, Sang‐Hyuk, Lee, Kun‐Gu, Chang, Bomi, Cheong, Eunji, Lee, C. Justin, Hwang, Dong‐Youn |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450125/ https://www.ncbi.nlm.nih.gov/pubmed/34323338 http://dx.doi.org/10.1111/cpr.13103 |
Ejemplares similares
-
Prospect of Human Pluripotent Stem Cell-Derived Neural Crest Stem Cells in Clinical Application
por: Zhu, Qian, et al.
Publicado: (2016) -
Generating trunk neural crest from human pluripotent stem cells
por: Huang, Miller, et al.
Publicado: (2016) -
Modeling brain and neural crest neoplasms with human pluripotent stem cells
por: Schloo, Cedar, et al.
Publicado: (2023) -
Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling
por: Kléber, Maurice, et al.
Publicado: (2005) -
PSA-NCAM-Negative Neural Crest Cells Emerging during Neural Induction of Pluripotent Stem Cells Cause Mesodermal Tumors and Unwanted Grafts
por: Lee, Dongjin R., et al.
Publicado: (2015)