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The combination of dextran sulphate and polyvinyl alcohol prevents excess aggregation and promotes proliferation of pluripotent stem cells in suspension culture

OBJECTIVES: For clinical applications of cell‐based therapies, a large quantity of human pluripotent stem cells (hPSCs) produced in standardized and scalable culture processes is required. Currently, microcarrier‐free suspension culture shows potential for large‐scale expansion of hPSCs; however, hP...

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Detalles Bibliográficos
Autores principales: Tang, Xianglian, Wu, Haibin, Xie, Jinghe, Wang, Ning, Chen, Qicong, Zhong, Zhiyong, Qiu, Yaqi, Wang, Jue, Li, Xiajing, Situ, Ping, Lai, Liangxue, Zern, Mark A, Chen, Honglin, Duan, Yuyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450127/
https://www.ncbi.nlm.nih.gov/pubmed/34390064
http://dx.doi.org/10.1111/cpr.13112