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LRPPRC regulates metastasis and glycolysis by modulating autophagy and the ROS/HIF1-α pathway in retinoblastoma

Retinoblastoma (RB) is the most common intraocular tumor among children. Leucine-rich pentatricopeptide repeat (PPR)-motif-containing protein (LRPPRC), a suppressor gene of autophagy, has been proven to play a regulatory role in tumor progression. However, little is known about functional roles and...

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Detalles Bibliográficos
Autores principales: Song, Kun, Li, Bin, Chen, Ying-Ying, Wang, Hua, Liu, Kang-Cheng, Tan, Wei, Zou, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450181/
https://www.ncbi.nlm.nih.gov/pubmed/34589577
http://dx.doi.org/10.1016/j.omto.2021.06.009