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Genetic Polymorphism of GABRG2 rs211037 is Associated with Drug Response and Adverse Drug Reactions to Valproic Acid in Chinese Southern Children with Epilepsy

BACKGROUND: Valproic acid (VPA) is recommended as a first-line treatment for children with epilepsy. GABRG2 polymorphism is found to be associated with epilepsy susceptibility and therapeutic response of anti-seizure medications (ASM); however, the role of GABRG2 in VPA treatment still remains unkno...

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Detalles Bibliográficos
Autores principales: Lu, Jieluan, Xia, Hanbing, Li, Wenzhou, Shen, Xianhuan, Guo, Huijuan, Zhang, Jianping, Fan, Xiaomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450188/
https://www.ncbi.nlm.nih.gov/pubmed/34552348
http://dx.doi.org/10.2147/PGPM.S329594