Cargando…
Genetic Polymorphism of GABRG2 rs211037 is Associated with Drug Response and Adverse Drug Reactions to Valproic Acid in Chinese Southern Children with Epilepsy
BACKGROUND: Valproic acid (VPA) is recommended as a first-line treatment for children with epilepsy. GABRG2 polymorphism is found to be associated with epilepsy susceptibility and therapeutic response of anti-seizure medications (ASM); however, the role of GABRG2 in VPA treatment still remains unkno...
Autores principales: | Lu, Jieluan, Xia, Hanbing, Li, Wenzhou, Shen, Xianhuan, Guo, Huijuan, Zhang, Jianping, Fan, Xiaomei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450188/ https://www.ncbi.nlm.nih.gov/pubmed/34552348 http://dx.doi.org/10.2147/PGPM.S329594 |
Ejemplares similares
-
Association of ABCB1 Polymorphisms with Efficacy and Adverse Drug Reactions of Valproic Acid in Children with Epilepsy
por: Zhu, Jiahao, et al.
Publicado: (2023) -
Association between the SLC6A11 rs2304725 and GABRG2 rs211037 polymorphisms and drug-resistant epilepsy: a meta-analysis
por: Hu, Xuemei, et al.
Publicado: (2023) -
AS3MT Polymorphism: A Risk Factor for Epilepsy Susceptibility and Adverse Drug Reactions to Valproic Acid and Oxcarbazepine Treatment in Children From South China
por: Fan, Xiaomei, et al.
Publicado: (2021) -
Pharmacogenetics-based population pharmacokinetic analysis and dose optimization of valproic acid in Chinese southern children with epilepsy: Effect of ABCB1 gene polymorphism
por: Shen, Xianhuan, et al.
Publicado: (2022) -
Analysis of GABRG2 C588T polymorphism in genetic epilepsy and evaluation of GABRG2 in drug treatment
por: Wang, Shitao, et al.
Publicado: (2021)