Epithelial–stromal cell interactions and extracellular matrix mechanics drive the formation of airway-mimetic tubular morphology in lung organoids

Complex human airway cellular organization where extracellular matrix (ECM) and epithelial and stromal lineages interact present challenges for organ study in vitro. Current in vitro lung models that focus on the lung epithelium do not represent complex airway morphology and cell-ECM interactions se...

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Detalles Bibliográficos
Autores principales: Güney, Tankut.G., Herranz, Alfonso Muinelo, Mumby, Sharon, Dunlop, Iain E., Adcock, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450245/
https://www.ncbi.nlm.nih.gov/pubmed/34585112
http://dx.doi.org/10.1016/j.isci.2021.103061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450245/
https://www.ncbi.nlm.nih.gov/pubmed/34585112
http://dx.doi.org/10.1016/j.isci.2021.103061

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