Pharmacological Rescue of the Brain Cortex Phenotype of Tbx1 Mouse Mutants: Significance for 22q11.2 Deletion Syndrome

OBJECTIVES: Tbx1 mutant mice are a widely used model of 22q11.2 deletion syndrome (22q11.2DS) because they manifest a broad spectrum of physical and behavioral abnormalities that is similar to that found in 22q11.2DS patients. In Tbx1 mutants, brain abnormalities include changes in cortical cytoarch...

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Detalles Bibliográficos
Autores principales: Favicchia, Ilaria, Flore, Gemma, Cioffi, Sara, Lania, Gabriella, Baldini, Antonio, Illingworth, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450345/
https://www.ncbi.nlm.nih.gov/pubmed/34552467
http://dx.doi.org/10.3389/fnmol.2021.663598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450345/
https://www.ncbi.nlm.nih.gov/pubmed/34552467
http://dx.doi.org/10.3389/fnmol.2021.663598

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