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Pharmacological Rescue of the Brain Cortex Phenotype of Tbx1 Mouse Mutants: Significance for 22q11.2 Deletion Syndrome

OBJECTIVES: Tbx1 mutant mice are a widely used model of 22q11.2 deletion syndrome (22q11.2DS) because they manifest a broad spectrum of physical and behavioral abnormalities that is similar to that found in 22q11.2DS patients. In Tbx1 mutants, brain abnormalities include changes in cortical cytoarch...

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Detalles Bibliográficos
Autores principales:	Favicchia, Ilaria, Flore, Gemma, Cioffi, Sara, Lania, Gabriella, Baldini, Antonio, Illingworth, Elizabeth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450345/ https://www.ncbi.nlm.nih.gov/pubmed/34552467 http://dx.doi.org/10.3389/fnmol.2021.663598

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