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Codon Optimization of Insect Odorant Receptor Genes May Increase Their Stable Expression for Functional Characterization in HEK293 Cells

Insect odorant receptor (OR) genes are routinely expressed in Human Embryonic Kidney (HEK) 293 cells for functional characterization (“de-orphanization”) using transient or stable expression. However, progress in this research field has been hampered because some insect ORs are not functional in thi...

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Detalles Bibliográficos
Autores principales: Roberts, Rebecca E., Yuvaraj, Jothi Kumar, Andersson, Martin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450354/
https://www.ncbi.nlm.nih.gov/pubmed/34552471
http://dx.doi.org/10.3389/fncel.2021.744401