Pyruvate Dehydrogenase Kinase Inhibitor Dichloroacetate Improves Host Control of Salmonella enterica Serovar Typhimurium Infection in Human Macrophages

Global increases in the prevalence of antimicrobial resistance highlight the urgent need for novel strategies to combat infectious diseases. Recent studies suggest that host metabolic pathways play a key role in host control of intracellular bacterial pathogens. In this study we explored the potenti...

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Detalles Bibliográficos
Autores principales: van Doorn, Cassandra L. R., Schouten, Gina K., van Veen, Suzanne, Walburg, Kimberley V., Esselink, Jeroen J., Heemskerk, Matthias T., Vrieling, Frank, Ottenhoff, Tom H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450447/
https://www.ncbi.nlm.nih.gov/pubmed/34552598
http://dx.doi.org/10.3389/fimmu.2021.739938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450447/
https://www.ncbi.nlm.nih.gov/pubmed/34552598
http://dx.doi.org/10.3389/fimmu.2021.739938

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