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PD-L1-Mediated Immunosuppression in Oral Squamous Cell Carcinoma: Relationship With Macrophage Infiltration and Epithelial to Mesenchymal Transition Markers

To date, immune check-point inhibitors (ICIs), particularly inhibitors of programmed cell death-1 (PD-1) and PD ligand-1 (PD-L1) have become prominent in cancer treatment and also improved life expectancy of cancer patients. As key regulators of PD-1/PD-L1 axis, the recruitment of tumor-associated m...

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Detalles Bibliográficos
Autores principales: Wu, Tiantian, Tang, Caijin, Tao, Renchuan, Yong, Xiangzhi, Jiang, Qiaozhi, Feng, Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450501/
https://www.ncbi.nlm.nih.gov/pubmed/34552581
http://dx.doi.org/10.3389/fimmu.2021.693881