Senescent Tissue-Resident Mesenchymal Stromal Cells Are an Internal Source of Inflammation in Human Osteoarthritic Cartilage

Human osteoarthritic cartilage contains not only chondrocytes (OACs), but also mesenchymal stromal cells (OA-MSCs), whose abundance increases during osteoarthritis (OA). However, it is not clear how OA-MSC contributes to OA pathogenesis. Here, we show that aging OA-MSC plays an important role in cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Wenguang, Brodsky, Alexander S., Feng, Meng, Liu, Yajun, Ding, Jing, Jayasuriya, Chathuraka T., Chen, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450518/
https://www.ncbi.nlm.nih.gov/pubmed/34552931
http://dx.doi.org/10.3389/fcell.2021.725071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450518/
https://www.ncbi.nlm.nih.gov/pubmed/34552931
http://dx.doi.org/10.3389/fcell.2021.725071

Ejemplares similares