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Properdin Deficiency Impairs Phagocytosis and Enhances Injury at Kidney Repair Phase Post Ischemia–Reperfusion

Properdin, a positive regulator of complement alternative pathway, participates in renal ischemia–reperfusion (IR) injury and also acts as a pattern-recognition molecule affecting apoptotic T-cell clearance. However, the role of properdin in tubular epithelial cells (TECs) at the repair phase post I...

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Detalles Bibliográficos
Autores principales: Wu, Yuanyuan, Zwaini, Zinah D., Brunskill, Nigel J., Zhang, Xinyue, Wang, Hui, Chana, Ravinder, Stover, Cordula M., Yang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450566/
https://www.ncbi.nlm.nih.gov/pubmed/34552582
http://dx.doi.org/10.3389/fimmu.2021.697760