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Transcriptome Analysis of Immune Receptor Activation and Energy Metabolism Reduction as the Underlying Mechanisms in Interleukin-6-Induced Skeletal Muscle Atrophy

BACKGROUND: Inflammation may trigger skeletal muscle atrophy induced by cancer cachexia. As a pro-inflammatory factor, interleukin-6 may cause skeletal muscle atrophy, but the underlying molecular mechanisms have not been explored. METHODS: In this experimental study, we used adult male ICR mice, we...

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Detalles Bibliográficos
Autores principales: Sun, Hualin, Sun, Junjie, Li, Ming, Qian, Lei, Zhang, Lilei, Huang, Ziwei, Shen, Yuntian, Law, Betty Yuen-Kwan, Liu, Liang, Gu, Xiaosong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450567/
https://www.ncbi.nlm.nih.gov/pubmed/34552592
http://dx.doi.org/10.3389/fimmu.2021.730070