Effect of Missed Doses on the Therapeutic Effect of Methotrexate for Rheumatoid Arthritis: A Pharmacokinetic Modeling Study

INTRODUCTION: Patients rarely, if ever, take their medications exactly as prescribed. The extent to which missed doses interfere with a drug’s therapeutic effect remains unclear. METHODS: After weekly oral dosing of methotrexate (MTX) for rheumatoid arthritis, its polyglutamate derivatives (MTXglu)...

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Detalles Bibliográficos
Autores principales: Morrison, Alan, Stauffer, Melissa E, Kaufman, Anna S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450605/
https://www.ncbi.nlm.nih.gov/pubmed/34552357
http://dx.doi.org/10.2147/OARRR.S329178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450605/
https://www.ncbi.nlm.nih.gov/pubmed/34552357
http://dx.doi.org/10.2147/OARRR.S329178

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