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Pulmonary Hypertension in Obese Mice Is Accompanied by a Reduction in PPAR-γ Expression in Pulmonary Artery

Obesity and insulin resistance (IR) are well-studied risk factors for systemic cardiovascular disease, but their impact on pulmonary hypertension (PH) is not well clarified. This study aims to investigate if diet-induced obesity induces PH and if peroxisome-proliferator-activated receptor (PPAR-γ) a...

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Detalles Bibliográficos
Autores principales: Gonçalves, Any Elisa de Souza Schmidt, Rocha, Guilherme Zweig, Marin, Rodrigo, Camargo, Rafael Ludemann, dos Santos, Andrey, do Carmo, Helison, Guadagnini, Dioze, Petrucci, Orlando, Moysés, Zenaide Providello, Salemi, Vera Maria Cury, Oliveira, Alexandre Gabarra, Saad, Mario José Abdalla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450870/
https://www.ncbi.nlm.nih.gov/pubmed/34552556
http://dx.doi.org/10.3389/fendo.2021.701994