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Pulmonary Hypertension in Obese Mice Is Accompanied by a Reduction in PPAR-γ Expression in Pulmonary Artery
Obesity and insulin resistance (IR) are well-studied risk factors for systemic cardiovascular disease, but their impact on pulmonary hypertension (PH) is not well clarified. This study aims to investigate if diet-induced obesity induces PH and if peroxisome-proliferator-activated receptor (PPAR-γ) a...
Autores principales: | Gonçalves, Any Elisa de Souza Schmidt, Rocha, Guilherme Zweig, Marin, Rodrigo, Camargo, Rafael Ludemann, dos Santos, Andrey, do Carmo, Helison, Guadagnini, Dioze, Petrucci, Orlando, Moysés, Zenaide Providello, Salemi, Vera Maria Cury, Oliveira, Alexandre Gabarra, Saad, Mario José Abdalla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450870/ https://www.ncbi.nlm.nih.gov/pubmed/34552556 http://dx.doi.org/10.3389/fendo.2021.701994 |
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