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Synthesis and antimicrobial activity of 1H-1,2,3-triazole and carboxylate analogues of metronidazole

Herein, a series of novel 1H-1,2,3-triazole and carboxylate derivatives of metronidazole (5a–i and 7a–e) were synthesized and evaluated for their antimicrobial activity in vitro. All the newly synthesized compounds were characterized by (1)H NMR, (13)C NMR, HRMS, and (19)F NMR (5b, 5c and 5h) spectr...

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Detalles Bibliográficos
Autores principales: Avula, Satya Kumar, Raza Shah, Syed, Al-Hosni, Khdija, U. Anwar, Muhammad, Csuk, Rene, Das, Biswanath, Al-Harrasi, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450958/
https://www.ncbi.nlm.nih.gov/pubmed/34621399
http://dx.doi.org/10.3762/bjoc.17.154