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Synthesis and antimicrobial activity of 1H-1,2,3-triazole and carboxylate analogues of metronidazole
Herein, a series of novel 1H-1,2,3-triazole and carboxylate derivatives of metronidazole (5a–i and 7a–e) were synthesized and evaluated for their antimicrobial activity in vitro. All the newly synthesized compounds were characterized by (1)H NMR, (13)C NMR, HRMS, and (19)F NMR (5b, 5c and 5h) spectr...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450958/ https://www.ncbi.nlm.nih.gov/pubmed/34621399 http://dx.doi.org/10.3762/bjoc.17.154 |