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Synthesis of O(6)-alkylated preQ(1) derivatives
A naturally occurring riboswitch can utilize 7-aminomethyl-O(6)-methyl-7-deazaguanine (m(6)preQ(1)) as cofactor for methyl group transfer resulting in cytosine methylation. This recently discovered riboswitch-ribozyme activity opens new avenues for the development of RNA labeling tools based on tail...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450960/ https://www.ncbi.nlm.nih.gov/pubmed/34621392 http://dx.doi.org/10.3762/bjoc.17.147 |