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Targeting active site residues and structural anchoring positions in terpene synthases

The sesterterpene synthase SmTS1 from Streptomyces mobaraensis contains several unusual residues in positions that are otherwise highly conserved. Site-directed mutagenesis experiments for these residues are reported that showed different effects, resulting in some cases in an improved catalytic act...

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Detalles Bibliográficos
Autores principales: Hou, Anwei, Dickschat, Jeroen S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8450962/
https://www.ncbi.nlm.nih.gov/pubmed/34621406
http://dx.doi.org/10.3762/bjoc.17.161