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Negative charge in the RACK1 loop broadens the translational capacity of the human ribosome

Although the roles of initiation factors, RNA binding proteins, and RNA elements in regulating translation are well defined, how the ribosome functionally diversifies remains poorly understood. In their human hosts, poxviruses phosphorylate serine 278 (S(278)) at the tip of a loop domain in the smal...

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Detalles Bibliográficos
Autores principales: Rollins, Madeline G., Shasmal, Manidip, Meade, Nathan, Astar, Helen, Shen, Peter S., Walsh, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451006/
https://www.ncbi.nlm.nih.gov/pubmed/34496247
http://dx.doi.org/10.1016/j.celrep.2021.109663