Aorta smooth muscle-on-a-chip reveals impaired mitochondrial dynamics as a therapeutic target for aortic aneurysm in bicuspid aortic valve disease

BACKGROUND: Bicuspid aortic valve (BAV) is the most common congenital cardiovascular disease in general population and is frequently associated with the development of thoracic aortic aneurysm (TAA). There is no effective strategy to intervene with TAA progression due to an incomplete understanding...

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Detalles Bibliográficos
Autores principales: Abudupataer, Mieradilijiang, Zhu, Shichao, Yan, Shiqiang, Xu, Kehua, Zhang, Jingjing, Luo, Shaman, Ma, Wenrui, Alam, Md Fazle, Tang, Yuyi, Huang, Hui, Chen, Nan, Wang, Li, Yan, Guoquan, Li, Jun, Lai, Hao, Wang, Chunsheng, Zhu, Kai, Zhang, Weijia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451027/
https://www.ncbi.nlm.nih.gov/pubmed/34486519
http://dx.doi.org/10.7554/eLife.69310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451027/
https://www.ncbi.nlm.nih.gov/pubmed/34486519
http://dx.doi.org/10.7554/eLife.69310

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