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Advances in chemical probing of protein O-GlcNAc glycosylation: structural role and molecular mechanisms

The addition of O-linked-β-d-N-acetylglucosamine (O-GlcNAc) onto serine and threonine residues of nuclear and cytoplasmic proteins is an abundant, unique post-translational modification governing important biological processes. O-GlcNAc dysregulation underlies several metabolic disorders leading to...

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Detalles Bibliográficos
Autores principales: Saha, Abhijit, Bello, Davide, Fernández-Tejada, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451060/
https://www.ncbi.nlm.nih.gov/pubmed/34338261
http://dx.doi.org/10.1039/d0cs01275k