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Advances in chemical probing of protein O-GlcNAc glycosylation: structural role and molecular mechanisms
The addition of O-linked-β-d-N-acetylglucosamine (O-GlcNAc) onto serine and threonine residues of nuclear and cytoplasmic proteins is an abundant, unique post-translational modification governing important biological processes. O-GlcNAc dysregulation underlies several metabolic disorders leading to...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451060/ https://www.ncbi.nlm.nih.gov/pubmed/34338261 http://dx.doi.org/10.1039/d0cs01275k |