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Natural Nano-Drug Delivery System in Coptidis Rhizoma Extract with Modified Berberine Hydrochloride Pharmacokinetics

PURPOSE: This study aimed to evaluate the pharmaceutical and pharmacokinetic effects of the natural nanoparticles (Nnps) isolated from Coptidis Rhizoma extract on berberine hydrochloride (BBR) and systematically explore the related mechanisms. METHODS: Firstly, Nnps were isolated from Coptidis Rhizo...

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Detalles Bibliográficos
Autores principales: Zhao, Jing, Zhao, Qing, Lu, Jing-Ze, Ye, Dan, Mu, Sheng, Yang, Xiao-Di, Zhang, Wei-Dong, Ma, Bing-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451076/
https://www.ncbi.nlm.nih.gov/pubmed/34552326
http://dx.doi.org/10.2147/IJN.S323685