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An emerging and variant viral promoter of HIV-1 subtype C exhibits low-level gene expression noise

BACKGROUND: We observe the emergence of several promoter-variant viral strains in India during recent years. The variant viral promoters contain additional copies of transcription factor binding sites present in the viral modulatory region or enhancer, including RBEIII, LEF-1, Ap-1 and/or NF-κB. The...

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Detalles Bibliográficos
Autores principales: Ali, Haider, Bhange, Disha, Mehta, Kavita, Gohil, Yuvrajsinh, Prajapati, Harshit Kumar, Byrareddy, Siddappa N., Buch, Shilpa, Ranga, Udaykumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451104/
https://www.ncbi.nlm.nih.gov/pubmed/34538278
http://dx.doi.org/10.1186/s12977-021-00572-2