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RNA m6A demethylase FTO-mediated epigenetic up-regulation of LINC00022 promotes tumorigenesis in esophageal squamous cell carcinoma

BACKGROUND: Long non-coding RNA (LncRNA) controls cell proliferation and plays a significant role in the initiation and progression of esophageal squamous cell carcinoma (ESCC). N6-methyladenosine (m6A) modification now is recognized as a master driver of RNA function to maintain homeostasis in canc...

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Detalles Bibliográficos
Autores principales: Cui, Yuanbo, Zhang, Chunyan, Ma, Shanshan, Li, Zhe, Wang, Wenjie, Li, Ya, Ma, Yingchao, Fang, Jiarui, Wang, Yaping, Cao, Wei, Guan, Fangxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451109/
https://www.ncbi.nlm.nih.gov/pubmed/34544449
http://dx.doi.org/10.1186/s13046-021-02096-1