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RNA m6A demethylase FTO-mediated epigenetic up-regulation of LINC00022 promotes tumorigenesis in esophageal squamous cell carcinoma
BACKGROUND: Long non-coding RNA (LncRNA) controls cell proliferation and plays a significant role in the initiation and progression of esophageal squamous cell carcinoma (ESCC). N6-methyladenosine (m6A) modification now is recognized as a master driver of RNA function to maintain homeostasis in canc...
Autores principales: | Cui, Yuanbo, Zhang, Chunyan, Ma, Shanshan, Li, Zhe, Wang, Wenjie, Li, Ya, Ma, Yingchao, Fang, Jiarui, Wang, Yaping, Cao, Wei, Guan, Fangxia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451109/ https://www.ncbi.nlm.nih.gov/pubmed/34544449 http://dx.doi.org/10.1186/s13046-021-02096-1 |
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