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Hierarchical cell-type-specific functions of caspase-11 in LPS shock and antibacterial host defense

Caspase-11 sensing of intracellular lipopolysaccharide (LPS) plays critical roles during infections and sepsis. However, the key cell types that sense intracellular LPS and their contributions to the host responses at the organismal level are not completely clear. Here, we show that macrophage/monoc...

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Detalles Bibliográficos
Autores principales: Kumari, Puja, Russo, Ashley J., Wright, Skylar S., Muthupalani, Sureshkumar, Rathinam, Vijay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451177/
https://www.ncbi.nlm.nih.gov/pubmed/33882312
http://dx.doi.org/10.1016/j.celrep.2021.109012