Small molecule kinase inhibitors enhance aminolevulinic acid-mediated protoporphyrin IX fluorescence and PDT response in triple negative breast cancer cell lines

Significance: We demonstrate that clinically used kinase inhibitors such as lapatinib can be used for enhancing aminolevulinic acid (ALA) for tumor fluorescence imaging and photodynamic therapy (PDT). Aim: ALA is used as a prodrug for protoporphyrin IX (PpIX) fluorescence-guided tumor resection and...

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Detalles Bibliográficos
Autores principales: Palasuberniam, Pratheeba, Kraus, Daniel, Mansi, Matthew, Howley, Richard, Braun, Alexander, Myers, Kenneth A., Chen, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2021
Materias:
Therapeutic
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451314/
https://www.ncbi.nlm.nih.gov/pubmed/34545713
http://dx.doi.org/10.1117/1.JBO.26.9.098002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451314/
https://www.ncbi.nlm.nih.gov/pubmed/34545713
http://dx.doi.org/10.1117/1.JBO.26.9.098002

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