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Small molecule kinase inhibitors enhance aminolevulinic acid-mediated protoporphyrin IX fluorescence and PDT response in triple negative breast cancer cell lines

Significance: We demonstrate that clinically used kinase inhibitors such as lapatinib can be used for enhancing aminolevulinic acid (ALA) for tumor fluorescence imaging and photodynamic therapy (PDT). Aim: ALA is used as a prodrug for protoporphyrin IX (PpIX) fluorescence-guided tumor resection and...

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Detalles Bibliográficos
Autores principales:	Palasuberniam, Pratheeba, Kraus, Daniel, Mansi, Matthew, Howley, Richard, Braun, Alexander, Myers, Kenneth A., Chen, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society of Photo-Optical Instrumentation Engineers 2021
Materias:	Therapeutic
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451314/ https://www.ncbi.nlm.nih.gov/pubmed/34545713 http://dx.doi.org/10.1117/1.JBO.26.9.098002

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