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Hsp70 modulates immune response in pancreatic cancer through dendritic cells

Heat shock protein 70 (Hsp70), a protein chaperone, is known to promote cell survival and tumor progression. However, its role in the tumor microenvironment (TME) is largely unknown. We specifically evaluated Hsp70 in the TME by implanting tumors in wild-type (WT) controls or Hsp70(−/-) animals, thu...

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Detalles Bibliográficos
Autores principales: Giri, Bhuwan, Sharma, Prateek, Jain, Tejeshwar, Ferrantella, Anthony, Vaish, Utpreksha, Mehra, Siddharth, Garg, Bharti, Iyer, Srikanth, Sethi, Vrishketan, Malchiodi, Zoe, Signorelli, Rossana, Jacob, Harrys K.C, George, John, Sahay, Preeti, Bava, Ejas P., Dawra, Rajinder, Ramakrishnan, Sundaram, Saluja, Ashok, Dudeja, Vikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451449/
https://www.ncbi.nlm.nih.gov/pubmed/34552825
http://dx.doi.org/10.1080/2162402X.2021.1976952