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Hsp70 modulates immune response in pancreatic cancer through dendritic cells
Heat shock protein 70 (Hsp70), a protein chaperone, is known to promote cell survival and tumor progression. However, its role in the tumor microenvironment (TME) is largely unknown. We specifically evaluated Hsp70 in the TME by implanting tumors in wild-type (WT) controls or Hsp70(−/-) animals, thu...
Autores principales: | Giri, Bhuwan, Sharma, Prateek, Jain, Tejeshwar, Ferrantella, Anthony, Vaish, Utpreksha, Mehra, Siddharth, Garg, Bharti, Iyer, Srikanth, Sethi, Vrishketan, Malchiodi, Zoe, Signorelli, Rossana, Jacob, Harrys K.C, George, John, Sahay, Preeti, Bava, Ejas P., Dawra, Rajinder, Ramakrishnan, Sundaram, Saluja, Ashok, Dudeja, Vikas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451449/ https://www.ncbi.nlm.nih.gov/pubmed/34552825 http://dx.doi.org/10.1080/2162402X.2021.1976952 |
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