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Ki20227 aggravates apoptosis, inflammatory response, and oxidative stress after focal cerebral ischemia injury

The survival of microglia depends on the colony-stimulating factor-1 receptor (CSF1R) signaling pathway under physiological conditions. Ki20227 is a highly selective CSF1R inhibitor that has been shown to change the morphology of microglia. However, the effects of Ki20227 on the progression of ische...

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Detalles Bibliográficos
Autores principales: Jiang, Cheng, Wang, Ze-Ning, Kang, Yu-Chen, Chen, Yi, Lu, Wei-Xin, Ren, Hai-Jun, Hou, Bo-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451550/
https://www.ncbi.nlm.nih.gov/pubmed/34100449
http://dx.doi.org/10.4103/1673-5374.314318