Neuroprotective effects of Alda-1 mitigate spinal cord injury in mice: involvement of Alda-1-induced ALDH2 activation-mediated suppression of reactive aldehyde mechanisms

Spinal cord injury (SCI) is associated with high production and excessive accumulation of pathological 4-hydroxy-trans-2-nonenal (4-HNE), a reactive aldehyde, formed by SCI-induced metabolic dysregulation of membrane lipids. Reactive aldehyde load causes redox alteration, neuroinflammation, neurodeg...

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Detalles Bibliográficos
Autores principales: Khan, Mushfiquddin, Qiao, Fei, Kumar, Pavan, Islam, S.M. Touhidul, Singh, Avtar K., Won, Jeseong, Singh, Inderjit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451565/
https://www.ncbi.nlm.nih.gov/pubmed/34100455
http://dx.doi.org/10.4103/1673-5374.314312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451565/
https://www.ncbi.nlm.nih.gov/pubmed/34100455
http://dx.doi.org/10.4103/1673-5374.314312

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