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Global DNA hypomethylation of Alu and LINE-1 transposable elements as an epigenetic biomarker of anti-tuberculosis drug-induced liver injury

Despite being highly effective, anti-tuberculosis (TB) drugs often induce adverse liver injury, anti-TB drug-induced liver injury (ATDILI), leading to treatment failure given no sensitive and selective ATDILI markers. Herein, we conducted a case–control association study to determine whether global...

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Detalles Bibliográficos
Autores principales: Udomsinprasert, Wanvisa, Sakuntasri, Wanchaloem, Jittikoon, Jiraphun, Chaikledkaew, Usa, Honsawek, Sittisak, Chantratita, Wasun, Wattanapokayakit, Sukanya, Mahasirimongkol, Surakameth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451674/
https://www.ncbi.nlm.nih.gov/pubmed/34467830
http://dx.doi.org/10.1080/22221751.2021.1976079