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Model‐informed drug repurposing: Viral kinetic modelling to prioritize rational drug combinations for COVID‐19

AIM: We hypothesized that viral kinetic modelling could be helpful to prioritize rational drug combinations for COVID‐19. The aim of this research was to use a viral cell cycle model of SARS‐CoV‐2 to explore the potential impact drugs, or combinations of drugs, that act at different stages in the vi...

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Detalles Bibliográficos
Autores principales: Dodds, Michael G., Krishna, Rajesh, Goncalves, Antonio, Rayner, Craig R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451752/
https://www.ncbi.nlm.nih.gov/pubmed/32693436
http://dx.doi.org/10.1111/bcp.14486