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Model‐informed drug repurposing: Viral kinetic modelling to prioritize rational drug combinations for COVID‐19
AIM: We hypothesized that viral kinetic modelling could be helpful to prioritize rational drug combinations for COVID‐19. The aim of this research was to use a viral cell cycle model of SARS‐CoV‐2 to explore the potential impact drugs, or combinations of drugs, that act at different stages in the vi...
Autores principales: | Dodds, Michael G., Krishna, Rajesh, Goncalves, Antonio, Rayner, Craig R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451752/ https://www.ncbi.nlm.nih.gov/pubmed/32693436 http://dx.doi.org/10.1111/bcp.14486 |
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