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SM04755, a small‐molecule inhibitor of the Wnt pathway, as a potential topical treatment for tendinopathy

The Wnt pathway is upregulated in tendinopathy, affecting inflammation and tenocyte differentiation. Given its potential role in tendinopathy, this signaling pathway may be a relevant target for treatment. The current study examined the therapeutic potential of SM04755, a topical, small‐molecule Wnt...

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Detalles Bibliográficos
Autores principales: Deshmukh, Vishal, Seo, Tim, O'Green, Alyssa L., Ibanez, Maureen, Hofilena, Brian, KC, Sunil, Stewart, Joshua, Dellamary, Luis, Chiu, Kevin, Ghias, Abdullah, Barroga, Charlene, Kennedy, Sarah, Tambiah, Jeyanesh, Hood, John, Yazici, Yusuf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451793/
https://www.ncbi.nlm.nih.gov/pubmed/33104243
http://dx.doi.org/10.1002/jor.24898