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Evaluation of Drug‐Drug Interaction Liability for Buprenorphine Extended‐Release Monthly Injection Administered by Subcutaneous Route

Buprenorphine extended‐release (BUP‐XR) formulation is a once‐monthly subcutaneous injection for the treatment of opioid use disorder (OUD). Buprenorphine undergoes extensive cytochrome P450 (CYP) 3A4 metabolism, leading to potential drug‐drug interactions (DDIs) as reported for sublingual buprenorp...

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Detalles Bibliográficos
Autores principales: Kharidia, Jahnavi, Howgate, Eleanor M., Laffont, Celine M., Liu, Yongzhen, Young, Malcolm A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451859/
https://www.ncbi.nlm.nih.gov/pubmed/33750027
http://dx.doi.org/10.1002/cpdd.934