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Development of a platform process for the production and purification of single‐domain antibodies

Single‐domain antibodies (sdAbs) offer the affinity and therapeutic value of conventional antibodies, with increased stability and solubility. Unlike conventional antibodies, however, sdAbs do not benefit from a platform manufacturing process. While successful production of a variety of sdAbs has be...

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Detalles Bibliográficos
Autores principales: Crowell, Laura E., Goodwine, Chaz, Holt, Carla S., Rocha, Lucia, Vega, Celina, Rodriguez, Sergio A., Dalvie, Neil C., Tracey, Mary K., Puntel, Mariana, Wigdorovitz, Andrés, Parreño, Viviana, Love, Kerry R., Cramer, Steven M., Love, J. Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451865/
https://www.ncbi.nlm.nih.gov/pubmed/33624832
http://dx.doi.org/10.1002/bit.27724