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Development of a platform process for the production and purification of single‐domain antibodies
Single‐domain antibodies (sdAbs) offer the affinity and therapeutic value of conventional antibodies, with increased stability and solubility. Unlike conventional antibodies, however, sdAbs do not benefit from a platform manufacturing process. While successful production of a variety of sdAbs has be...
Autores principales: | Crowell, Laura E., Goodwine, Chaz, Holt, Carla S., Rocha, Lucia, Vega, Celina, Rodriguez, Sergio A., Dalvie, Neil C., Tracey, Mary K., Puntel, Mariana, Wigdorovitz, Andrés, Parreño, Viviana, Love, Kerry R., Cramer, Steven M., Love, J. Christopher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451865/ https://www.ncbi.nlm.nih.gov/pubmed/33624832 http://dx.doi.org/10.1002/bit.27724 |
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